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protein-coding gene in the species Homo sapiens

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About CLU

Clusterin is a protein that in humans is encoded by the CLU gene on chromosome 8. CLU is an extracellular molecular chaperone which binds to misfolded proteins in body fluids to neutralise their toxicity and mediate their cellular uptake by receptor-mediated endocytosis. Once internalised by cells, complexes between CLU and misfolded proteins are trafficked to lysosomes where they are degraded. CLU is involved in many diseases including neurodegenerative diseases, cancers, inflammatory diseases, and aging.

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Landgrab: Patroclus Edition

Paint the map. Hold the line. Take the world. Now starring the Patroclus parody.